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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 MED12 (NM_005120) cDNA克隆
人 MED12 (NM_005120) cDNA克隆
人 MED12 (NM_005120) cDNA克隆
  • 商品货号：FC172577
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    • accession：NM_005120
    • 基因别名：MED12
    • 基因描述：Homo sapiens mediator complex subunit 12 (MED12), mRNA.
    • 载体：现货载体
    • CDS区长度：6534
    • 翻译后氨基酸长度：2177
    • 基因简介：The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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