细胞信息
发货规格	1×10⁶
别名	EMT-6; Experimental Mammary Tumour-6
形态	上皮细胞样
生长特性	贴壁
培养条件	DMEM+10%FBS+1%P/S
冻存条件	90%FBS+10%DMSO
传代方式	胰酶消化
传代比例	1:2~1:4
换液频率	每周2~3次
生物安全等级	1
细胞背景
种属	小鼠
组织来源	乳腺
肿瘤类型	乳腺恶性肿瘤
供体信息	BALB/cCRGL.雌性小鼠
背景描述	EMT6 细胞系是一种小鼠乳腺癌细胞系，广泛用于癌症研究，尤其是与乳腺癌相关的研究。EMT6 细胞起源于 BALB/c 小鼠的自发性肿瘤，在体外和体内均用于分析肿瘤发生、转移和化疗耐药性。这些细胞的特点是当移植到免疫功能正常的小鼠中时能够迅速形成肿瘤，使其成为研究肿瘤免疫和抗癌疗法疗效的理想模型。
遗传背景
致瘤性	Yes， forms solid tumors in some sublines of BALB/c mice
核型	This is a human cell line with near-diploid chromosome counts. The modal chromosome number was 47， occurring in 36% of cells. The rate of cells with a higher ploidy count was 3.9%. Twelve markers were common to most cells. Among them were del(1) (q32.1)， der (5)t(5;13) (p15.33;q11)， i(5p)， der(1)t(1;?) (p34.3;?) and der (6)t(6;7) (p25.3;q21.2). All markers were present in single copy per cell. Normal N1 and N6 were absent. There were two normal X chromosomes. No other abnormalities were detected.

STR鉴定

STR位点信息

STR鉴定图

Mouse STR 1-1	15
Mouse STR 1-2	17,18
Mouse STR 2-1	16
Mouse STR 3-2	14
Mouse STR 4-2	21.3
Mouse STR 5-5	13,15
Mouse STR 6-4	18
Mouse STR 6-7	12
Mouse STR 7-1	25.2
Mouse STR 8-1	13
Mouse STR 11-2	18
Mouse STR 12-1	16
Mouse STR 13-1	16.2
Mouse STR 15-3	22.3,23.3
Mouse STR 17-2	16
Mouse STR 18-3	18,19
Mouse STR 19-2	13
Mouse STR X-1	24