• 名称：Sorafenib (Nexavar)
• 简介：Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.
• CASNO：475207-59-1
• 分子式：C21H16ClF3N4O3.C7H8O3S
• 分子量：637
• SMILES：CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
• 保持条件：at -20°C 3 years Powder
• 同名：Bay 43-9006
• 纯度：>98%
• 应用：Raf inhibitor
• 作用机制：Inhibitor