- 名称:Linifanib (ABT-869)
- 简介:Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively.
- CASNO:796967-16-3
- 分子式:C21H18FN5O
- 分子量:375.4
- SMILES:CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
- 保持条件:at -20°C 3 years Powder
- 同名:ABT869, ABT-869
- 纯度:>98%
- 应用:VEGFR/PDGFR inhibitor
- 作用机制:Inhibitor