• 名称：Cerubidine (Daunorubicin HCl, Rubidomycin HCl)
• 简介：Cerubidine (Daunorubicin HCl, Rubidomycin HCl) interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the progression of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription. It stabilizes the topoisomerase II complex after it has broken the DNA chain for replication, preventing the DNA double helix from being resealed and thereby stopping the process of replication.
• CASNO：23541-50-6
• 分子式：C27H29NO10.HCl
• 分子量：564
• SMILES：C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
• 保持条件：at -20°C 3 years Powder
• 同名：Daunorubicin HCl, Rubidomycin HCl
• 纯度：>98%
• 应用：Topoisomerase inhibitor
• 作用机制：Inhibitor