- 名称:Dovitinib Dilactic acid (TKI258 Dilactic acid)
- 简介:Dovitinib is a small-molecule multitargeted receptor tyrosine kinase inhibitor, which inhibits Ba/F3 cells transformed to IL3 independence by ZNF198-FGFR1 or BCR-FGFR1 with IC50 values of 150 nM and 90 nM, respectively.
- CASNO:852433-84-2
- 分子式:C21H21FN6O.2C3H6O3
- 分子量:572.6
- SMILES:CC(C(=O)O)O.CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4C(=C5C(=NC4=O)C=CC=C5F)N)/N3
- 保持条件:at -20°C 3 years Powder
- 同名:CHIR-258, TKI258
- 纯度:>98%
- 应用:RTK inhibitor
- 作用机制:Inhibitor