• 名称：Canertinib (CI-1033)
• 简介：Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM).
• CASNO：267243-28-7
• 分子式：C24H25ClFN5O3
• 分子量：485.9
• SMILES：C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
• 保持条件：at -20°C 3 years Powder
• 同名：CI-1033, CI1033, PD-183805
• 纯度：>98%
• 应用：HER2/ErbB2 inhibitor
• 作用机制：Inhibitor