- 名称:PD184352 (CI-1040)
- 简介:PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2.
- CASNO:212631-79-3
- 分子式:C17H14ClF2IN2O2
- 分子量:478.7
- SMILES:C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:CI-1040
- 纯度:>98%
- 应用:MEK1/2 inhibitor
- 作用机制:Inhibitor