- 名称:Cryptotanshinone
- 简介:Cryptotanshinone, a natural compound isolated from the roots of Salvia miltiorrhiza Bunge (Danshen), dramatically blocks STAT3 Tyr705 phosphorylation but not STAT3 Ser727 phosphorylation in DU145 cells, and significantly inhibits JAK2 phosphorylation with IC50 of ~5 μM without affecting the phosphorylation of upstream kinases c-Src and EGFR.
- CASNO:35825-57-1
- 分子式:C19H20O3
- 分子量:296.4
- SMILES:C[C@H]1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
- 保持条件:at -20°C 3 years Powder
- 同名:Tanshinone
- 纯度:>98%
- 应用:Stat3 inhibitor
- 作用机制:Inhibitor