- 名称:CYT997 (Lexibulin)
- 简介:CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.
- CASNO:917111-44-5
- 分子式:C24H30N6O2
- 分子量:434.5
- SMILES:CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC
- 保持条件:at -20°C 3 years Powder
- 同名:CYT-997, Lexibulin
- 纯度:>98%
- 应用:Microtubule Inhibitor
- 作用机制:Inhibitor