• 名称：Daphnetin
• 简介：Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 ?M), PKA (IC50 = 9.33 ?M), and PKC (IC50 = 25 ?M), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.
• CASNO：486-35-1
• 分子式：C9H6O4
• 分子量：178.1
• SMILES：C1=CC(=C(C2=C1C=CC(=O)O2)O)O
• 保持条件：at -20°C 3 years Powder
• 同名：7,8-dihydroxycoumarin
• 纯度：>98%
• 应用：EGFR, PKA,PKC inhibitor
• 作用机制：Inhibitor