• 名称：Etoposide (VP-16)
• 简介：Etoposide forms a ternary complex with DNA and the topoisomerase II enzyme (which aids in DNA unwinding), prevents re-ligation of the DNA strands, and by doing so causes DNA strands to break. Therefore, this causes errors in DNA synthesis and promotes apoptosis of the cancer cell.
• CASNO：33419-42-0
• 分子式：C29H32O13
• 分子量：588.6
• SMILES：C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
• 保持条件：at -20°C 3 years Powder
• 同名：VP16, Vepesid, etoposide phosphate
• 纯度：>98%
• 应用：Topoisomerase II inhibitor
• 作用机制：Inhibitor