• 名称：JNJ-7706621
• 简介：JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.
• CASNO：443797-96-4
• 分子式：C15H12F2N6O3S
• 分子量：394.4
• SMILES：C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
• 保持条件：at -20°C 3 years Powder
• 同名：JNJ7706621
• 纯度：>98%
• 应用：CDK/Aurora A/B Inhibitor
• 作用机制：Inhibitor