- 名称:KRN 633
- 简介:KRN 633 is a cell-permeable, reversible, ATP-competitive VEGFR kinase inhibitor that inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 μM and 4.33 μM, respectively) and inactive towards 17 other kinases (IC50 ≥ 10 μM).
- CASNO:286370-15-8
- 分子式:C20H21ClN4O4
- 分子量:416.9
- SMILES:CCCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC3=CC(=C(C=C32)OC)OC)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:KRN633, KRN-633
- 纯度:>98%
- 应用:VEGFR Inhibitor
- 作用机制:Inhibitor