• 名称：LDE225 (NVP-LDE225, Sonidegib)
• 简介：LDE225 (NVP-LDE225) is a potent, selective and orally bioavailable Smoothened (SMO) antagonist that inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO).
• CASNO：956697-53-3
• 分子式：C26H26F3N3O3
• 分子量：485.5
• SMILES：C[C@@H]1CN(C[C@@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F
• 保持条件：at -20°C 3 years Powder
• 同名：LDE-225
• 纯度：>98%
• 应用：Smo Antagonist
• 作用机制：Antagonist