- 名称:Mubritinib (TAK 165)
- 简介:Mubritinib (TAK 165) is a potent EGFR and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 ?M, respectively. Mubritinib(TAK 165) also inhibits p33cdk2 and p33cdk5.
- CASNO:366017-09-6
- 分子式:C25H23F3N4O2
- 分子量:468.5
- SMILES:C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)/C=C/C4=CC=C(C=C4)C(F)(F)F
- 保持条件:at -20°C 3 years Powder
- 同名:TAK-165, TAK165
- 纯度:>98%
- 应用:HER2/ErbB2 inhibitor
- 作用机制:Inhibitor