- 名称:SB 525334
- 简介:SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells
- CASNO:356559-20-1
- 分子式:C21H21N5
- 分子量:343.4
- SMILES:CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3
- 保持条件:at -20°C 3 years Powder
- 同名:SB-525334, SB525334
- 纯度:>98%
- 应用:ALK Inhibitor
- 作用机制:Inhibitor