• 名称：SGI-1776 (free base)
• 简介：SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.
• CASNO：1025065-69-3
• 分子式：C20H22F3N5O
• 分子量：405.4
• SMILES：CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
• 保持条件：at -20°C 3 years Powder
• 同名：SGI1776
• 纯度：>98%
• 应用：PIM1 Inhibitor
• 作用机制：Inhibitor