• 名称：Sitagliptin phosphate monohydrate
• 简介：Sitagliptin phosphate is an anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
• CASNO：654671-77-9
• 分子式：C16H15F6N5O.H3PO4.H2O
• 分子量：523.3
• SMILES：C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
• 保持条件：at -20°C 3 years Powder
• 同名：Januvia, MK-0431
• 纯度：>98%
• 应用：DDP-4 inhibitor
• 作用机制：Inhibitor