- 名称:WP1130 (Degrasyn)
- 简介:WP1130 (Degrasyn) is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells.
- CASNO:856243-80-6
- 分子式:C19H18BrN3O
- 分子量:384.3
- SMILES:CCC[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N
- 保持条件:at -20°C 3 years Powder
- 同名:WP-1130, Degrasyn
- 纯度:>98%
- 应用:DUB/Bcr/ABL Inhibitor
- 作用机制:Inhibitor