- 名称:WYE-354
- 简介:WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of PI3K α (IC50 = 1026 nM) and other kinases.
- CASNO:1062169-56-5
- 分子式:C24H29N7O5
- 分子量:495.5
- SMILES:COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
- 保持条件:at -20°C 3 years Powder
- 同名:WYE354
- 纯度:>98%
- 应用:mTOR Inhibitor
- 作用机制:Inhibitor