• 名称：ZM-447439
• 简介：ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
• CASNO：331771-20-1
• 分子式：C29H31N5O4
• 分子量：513.6
• SMILES：COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
• 保持条件：at -20°C 3 years Powder
• 同名：ZM447439
• 纯度：>98%
• 应用：Aurora Kinase inhibitor
• 作用机制：Inhibitor