- 名称:NVP-AEW541
- 简介:NVP-AEW541 is a selective IGF-1R kinase inhibitor that inhibits the autophosphorylation activity of IGF-1R (IC50 = 0.086 uM) and prevents IGF-1-mediated survival and proliferation of MCF-7 cells (IC50 = 0.16 and 1.64 uM, respectively).
- CASNO:475489-16-8
- 分子式:C27H29N5O
- 分子量:439.6
- SMILES:C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
- 保持条件:at -20°C 3 years Powder
- 同名:AEW541
- 纯度:>98%
- 应用:IGF-1R inhibitor
- 作用机制:Inhibitor