• 名称：GDC-0980 (Apitolisib, RG7422)
• 简介：GDC-0980 (RG7422) is a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms, respectively.
• CASNO：1032754-93-0
• 分子式：C23H30N8O3S
• 分子量：498.6
• SMILES：CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)C(=O)[C@H](C)O
• 保持条件：at -20°C 3 years Powder
• 同名：GDC0980
• 纯度：>98%
• 应用：mTOR/PI3K Inhibitor
• 作用机制：Inhibitor