- 名称:INCB018424 (Ruxolitinib)
- 简介:INCB018424 is a potent and selective inhibitor of Janus-associated kinase (JAK) 1 and 2, with IC50 to be 2.7, 4.5 and 332 nM for JAK1, JAK2 and JAK3 respectively;
- CASNO:941678-49-5
- 分子式:C17H18N6
- 分子量:306.4
- SMILES:C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
- 保持条件:at -20°C 3 years Powder
- 同名:Ruxolitinib, INCB18424
- 纯度:>98%
- 应用:JAK1/2 Inhibitor
- 作用机制:Inhibitor