• 名称：MK-0812
• 简介：MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes and low nM in the chemotaxis assay. It has good PK profiles in preclinical species and demonstrated efficacy in animal models.
• CASNO：624733-88-6
• 分子式：C24H34F3N3O3
• 分子量：469.5
• SMILES：CC(C)[C@@]1(CC[C@H](C1)N[C@H]2CCOC[C@H]2OC)C(=O)N3CCC4=NC=C(C=C4C3)C(F)(F)F
• 保持条件：at -20°C 3 years Powder
• 同名：MK0812
• 纯度：>98%
• 应用：CCR2 antagonist
• 作用机制：Antagonist