• 名称：INCB28060
• 简介：INCB28060, a novel inhibitor of c-MET kinase. INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10,000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines.
• CASNO：1029712-80-8
• 分子式：C23H17FN6O
• 分子量：412.4
• SMILES：CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F
• 保持条件：at -20°C 3 years Powder
• 同名：INCB-28060, INC-280, INC280
• 纯度：>98%
• 应用：c-MET Inhibitor
• 作用机制：Inhibitor