- 名称:AT-406 (SM-406, ARRY-334543)
- 简介:AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins, including X chromosome-linked IAP (XIAP), the cellular IAPs 1 (c-IAP1) and 2 (c-IAP2) and melanoma inhibitor of apoptosis protein (ML-IAP).
- CASNO:1071992-99-8
- 分子式:C32H43N5O4
- 分子量:561.71
- SMILES:C[C@@H](C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)CC(C)C)NC
- 保持条件:at -20°C 3 years Powder
- 同名:AT406, SM-406, ARRY-334543
- 纯度:>98%
- 应用:IAP inhibitor
- 作用机制:Inhibitor