• 名称：AZ 3146
• 简介：AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.
• CASNO：1124329-14-1
• 分子式：C24H32N6O3
• 分子量：452.55
• SMILES：CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC
• 保持条件：at -20°C 3 years Powder
• 同名：AZ-3146
• 纯度：>98%
• 应用：Mps1 inhibitor
• 作用机制：Inhibitor