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NSC-207895 (XI-006)
NSC-207895 (XI-006)
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  • 商品货号:A11179
  • 名称:NSC-207895 (XI-006)
  • 简介:NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A549 cells (1 to 10 µM for 16 to 24 h) by suppressesing MDMX promoter transcription activity (IC50 = 2.5 µM in HT1080 cells), leading to enhanced p53 stabilization and activation.
  • CASNO:58131-57-0
  • 分子式:C11H13N5O4
  • 分子量:279.25
  • SMILES:CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
  • 保持条件:at -20°C 3 years Powder
  • 同名:NSC207895
  • 纯度:>98%
  • 应用:MDMX Inhibitor
  • 作用机制:Inhibitor