- 名称:NSC-207895 (XI-006)
- 简介:NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A549 cells (1 to 10 µM for 16 to 24 h) by suppressesing MDMX promoter transcription activity (IC50 = 2.5 µM in HT1080 cells), leading to enhanced p53 stabilization and activation.
- CASNO:58131-57-0
- 分子式:C11H13N5O4
- 分子量:279.25
- SMILES:CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
- 保持条件:at -20°C 3 years Powder
- 同名:NSC207895
- 纯度:>98%
- 应用:MDMX Inhibitor
- 作用机制:Inhibitor