- 名称:LDN193189
- 简介:LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.
- CASNO:1062368-24-4
- 分子式:C25H22N6
- 分子量:406.48
- SMILES:C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3
- 保持条件:at -20°C 3 years Powder
- 同名:LDN-193189
- 纯度:>98%
- 应用:ALK inhibitor
- 作用机制:Inhibitor