• 名称：Exatecan mesylate
• 简介：Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
• CASNO：171335-80-1
• 分子式：C25H26FN3O7S
• 分子量：531.6
• SMILES：CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
• 保持条件：at -20°C 3 years Powder
• 同名：DX 8951, DX8951
• 纯度：>98%
• 应用：Topoisomerase I inhibitor
• 作用机制：Inhibitor