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Exatecan mesylate
Exatecan mesylate
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  • 商品货号:A11231
  • 名称:Exatecan mesylate
  • 简介:Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
  • CASNO:171335-80-1
  • 分子式:C25H26FN3O7S
  • 分子量:531.6
  • SMILES:CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
  • 保持条件:at -20°C 3 years Powder
  • 同名:DX 8951, DX8951
  • 纯度:>98%
  • 应用:Topoisomerase I inhibitor
  • 作用机制:Inhibitor