• 名称：TAK-285
• 简介：TAK-285 is an investigational HER2/EGFR inhibitor that penetrates the CNS in Rats with an Intact Blood Brain Barrier (BBB). TAK-285 has inhibitory activity against HER2 and EGFR kinases with IC50 values for HER2 and EGFR of 17 nmol/L (95% CI 12-24) and 23 nmol/L (95% CI 18-30), respectively.
• CASNO：871026-44-7
• 分子式：C26H25ClF3N5O3
• 分子量：548
• SMILES：CC(C)(CC(=O)NCCN1C=CC2=C1C(=NC=N2)NC3=CC(=C(C=C3)OC4=CC=CC(=C4)C(F)(F)F)Cl)O
• 保持条件：at -20°C 3 years Powder
• 同名：TAK285
• 纯度：>98%
• 应用：HER2/EGFR inhibitor
• 作用机制：Inhibitor