- 名称:Cobicistat (GS-9350)
- 简介:Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate.
- CASNO:1004316-88-4
- 分子式:C40H53N7O5S2
- 分子量:766
- SMILES:CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5
- 保持条件:at -20°C 3 years Powder
- 同名:GS9350
- 纯度:>98%
- 应用:CYP3A Inhibitor
- 作用机制:Inhibitor