• 名称：Dovitinib (TKI-258)
• 简介：Dovitinib is a small-molecule multitargeted receptor tyrosine kinase inhibitor, which inhibits Ba/F3 cells transformed to IL3 independence by ZNF198-FGFR1 or BCR-FGFR1 with IC50 values of 150 nM and 90 nM, respectively.
• CASNO：405169-16-6
• 分子式：C21H21FN6O
• 分子量：392.4
• SMILES：CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C4/C(=C5C(=NC4=O)C=CC=C5F)N)/N3
• 保持条件：at -20°C 3 years Powder
• 同名：CHIR-258, CHIR258, TKI258
• 纯度：>98%
• 应用：RTK inhibitor
• 作用机制：Inhibitor