- 名称:FMK
- 简介:FMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
- CASNO:821794-92-7
- 分子式:C18H19FN4O2
- 分子量:342.37
- SMILES:CC1=CC=C(C=C1)C2=C(N(C3=C2C(=NC=N3)N)CCCO)C(=O)CF
- 保持条件:at -20°C 3 years Powder
- 同名:N/A
- 纯度:>98%
- 应用:RSK inhibitor
- 作用机制:Inhibitor