- 名称:TC-E 5001
- 简介:TC-E 5001 is dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28 nM for TNKS1 and TNKS2 respectively, IC50 = 33 nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19 uM). Inhibits Wnt signaling and stabilizes Axin2 levels.
- CASNO:865565-29-3
- 分子式:C20H19N5O3S
- 分子量:409.46
- SMILES:CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3
- 保持条件:at -20°C 3 years Powder
- 同名:TC-E5001, TC-E-5001
- 纯度:>98%
- 应用:TNKS inhibitor
- 作用机制:Inhibitor