- 名称:Motesanib (AMG706)
- 简介:Motesanib (AMG706) is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors with IC?? values of 2 nM (VEGFR1), 3 nM (VEGFR2), 6 nM (VEGFR3), 84 nM (PDGFR), and 8 nM (Kit).
- CASNO:453562-69-1
- 分子式:C22H23N5O
- 分子量:373.45
- SMILES:CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
- 保持条件:at -20°C 3 years Powder
- 同名:AMG 706, AMG-706
- 纯度:>98%
- 应用:VEGFR Inhibitor
- 作用机制:Inhibitor