- 名称:PSI-7977
- 简介:PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).
- CASNO:1190307-88-0
- 分子式:C22H29FN3O9P
- 分子量:529.45
- SMILES:C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
- 保持条件:at -20°C 3 years Powder
- 同名:Sofosbuvir, PSI7977, GI-7977
- 纯度:>98%
- 应用:HCV Nucleotide Inhibitor
- 作用机制:Inhibitor