- 名称:SB 239063
- 简介:SB 239063 is a potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. SB 239063 reduces inflammatory cytokine production and is neuroprotective following oral administration in vivo.
- CASNO:193551-21-2
- 分子式:C20H21FN4O2
- 分子量:368.4
- SMILES:COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
- 保持条件:at -20°C 3 years Powder
- 同名:SB239063, SB-239063
- 纯度:>98%
- 应用:p38 MAPK inhibitor
- 作用机制:Inhibitor