- 名称:T0070907
- 简介:T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.
- CASNO:313516-66-4
- 分子式:C12H8ClN3O3
- 分子量:277.66
- SMILES:ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O
- 保持条件:at -20°C 3 years Powder
- 同名:T 0070907
- 纯度:>98%
- 应用:PPAR-γ antagonist
- 作用机制:Antagonist