• 名称：Compound 401
• 简介：Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (IC50 = 5.3 μM).
• CASNO：168425-64-7
• 分子式：C16H15N3O2
• 分子量：281.31
• SMILES：C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2
• 保持条件：at -20°C 3 years Powder
• 同名：N/A
• 纯度：>98%
• 应用：DNA-PK inhibitor
• 作用机制：Inhibitor