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PF 670462
PF 670462
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  • 商品货号:A11781
  • 名称:PF 670462
  • 简介:Potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.
  • CASNO:950912-80-8
  • 分子式:C19H20FN5.2HCl
  • 分子量:410.3
  • SMILES:C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl
  • 保持条件:at -20°C 3 years Powder
  • 同名:PF670462
  • 纯度:>98%
  • 应用:Casein kinase inhibitor
  • 作用机制:Inhibitor