• 名称：PF 670462
• 简介：Potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.
• CASNO：950912-80-8
• 分子式：C19H20FN5.2HCl
• 分子量：410.3
• SMILES：C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl
• 保持条件：at -20°C 3 years Powder
• 同名：PF670462
• 纯度：>98%
• 应用：Casein kinase inhibitor
• 作用机制：Inhibitor