- 名称:IOX 2
- 简介:IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.
- CASNO:931398-72-0
- 分子式:C19H16N2O5
- 分子量:352.3
- SMILES:C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
- 保持条件:at -20°C 3 years Powder
- 同名:IOX-2, IOX2
- 纯度:>98%
- 应用:HIF-PHD inhibitor
- 作用机制:Inhibitor