- 名称:Gambogic acid
- 简介:Gambogic acid is a natural product isolated from the Garcinia hanburyi tree. Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
- CASNO:2752-65-0
- 分子式:C38H44O8
- 分子量:628.75
- SMILES:CC(=CCC[C@@]1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4=C[C@@H]5C[C@@H]6[C@@]4(O3)[C@](C5=O)(OC6(C)C)C/C=C(/C)C(=O)O)CC=C(C)C)C)C
- 保持条件:at -20°C 3 years Powder
- 同名:N/A
- 纯度:>98%
- 应用:Bcl-2 inhibitor