• 名称：FTI 277
• 简介：FTI 276 is an inhibitor that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 μM respectively) and disrupts constitutive H-Ras-specific actvation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines.
• CASNO：170006-73-2
• 分子式：C22H29N3O3S2.C2HF3O2
• 分子量：561.64
• SMILES：CSCC[C@H](NC(=O)C1CCC(NC[C@@H](N)CS)CC1C1CCCCC1)C(=O)OC.OC(=O)C(F)(F)F
• 保持条件：at -20°C 3 years Powder
• 同名：FTI-277,FTI277
• 纯度：>98%
• 应用：FTase inhibitor
• 作用机制：Inhibitor