- 名称:Cilengitide trifluoroacetate
- 简介:Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
- CASNO:199807-35-7
- 分子式:C29H41N8O9F3
- 分子量:702.7
- SMILES:CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O
- 保持条件:at -20°C 3 years Powder
- 同名:EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
- 纯度:>98%
- 应用:Integrin inhibitor
- 作用机制:Inhibitor