- 名称:MKT 077
- 简介:Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.
- CASNO:147366-41-4
- 分子式:C21H22ClN3OS2
- 分子量:432
- SMILES:CCN1/C(=C/C2=CC=CC=[N+]2CC)/S/C(=C/3N(C4=CC=CC=C4S3)C)/C1=O.[Cl-]
- 保持条件:at -20°C 3 years Powder
- 同名:MKT077, MKT-077
- 纯度:>98%
- 应用:HSP70 Inhibitor
- 作用机制:Inhibitor