- 名称:IPI-145 (Duvelisib, INK1197)
- 简介:IPI-145, also known as INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.
- CASNO:1201438-56-3
- 分子式:C22H17ClN6O
- 分子量:416.86
- SMILES:C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
- 保持条件:at -20°C 3 years Powder
- 同名:IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197
- 纯度:>98%
- 应用:PI3K-δ/PI3K-γ inhibitor
- 作用机制:Inhibitor