• 名称：BMS 299897
• 简介：BMS 299897 is an orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo.
• CASNO：290315-45-6
• 分子式：C24H21ClF3NO4S
• 分子量：511.94
• SMILES：C[C@H](C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
• 保持条件：at -20°C 3 years Powder
• 同名：BMS 299897
• 纯度：>98%
• 应用：γ-secretase inhibitor
• 作用机制：Inhibitor